• Author: Alexander C. Kline
Clear all

Sex differences in treatment outcomes among U.S. service members with comorbid PTSD and MDD

Abstract: BACKGROUND: Posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) are prevalent and deleterious conditions that commonly co-occur among service …

Depression-related moderators of treatment outcomes in a clinical trial for service members with comorbid PTSD and MDD

Abstract: Major depressive disorder (MDD) frequently co-occurs with posttraumatic stress disorder (PTSD), and this comorbidity is linked to reduced PTSD treatment response, yet …

Treatment for co-occurring posttraumatic stress disorder and substance use disorders among Veterans and civilians: A test of causally moderated comparative effectiveness

Abstract: Objective: The prevalence and negative sequelae of co-occurring posttraumatic stress disorder and substance use disorder (PTSD + SUD) are well documented. Findings from …

Sudden gains in cognitive processing therapy with and without behavioral activation among service members with comorbid PTSD and MDD

Abstract: Sudden gains—large, rapid, and stable symptom reductions during treatment—are associated with better patient outcomes. Little is known about sudden gains among …

Reduction in reintegration stress among post-9/11 Veterans in a clinical trial for trauma-related guilt

Abstract: Reintegration stress is commonly reported by returning Veterans with post-trauma distress and associated with mental health and functioning difficulties. Interventions …

Was it helpful? Treatment outcomes and practice assignment adherence and helpfulness among US service members with posttraumatic stress disorder (PTSD) and major depressive disorder (MDD)

Abstract: Practice assignments (i.e. homework) are a key component in cognitive behavioral therapies that predict treatment outcomes for posttraumatic stress disorder (PTSD) and …

Residual symptoms following trauma-focused treatment for comorbid posttraumatic stress disorder and major depressive disorder

Abstract: Despite effective psychotherapy options for posttraumatic stress disorder (PTSD), some patients do not fully respond, and even among those reporting substantial …

Comparison of crisis response planning and treatment as usual for active duty service members at risk for suicide: Study protocol for a stepped-wedge cluster randomized trial in a military treatment facility

Abstract: Background: Suicide is one of the leading causes of death among U.S. service members, and rates of suicide among military personnel have increased over the past two …

Dropout in a clinical trial for comorbid PTSD and MDD among US service members: Are pretreatment characteristics predictive?

Abstract: OBJECTIVE: Despite effective treatment options for posttraumatic stress disorder (PTSD), many patients do not complete therapy. This includes U.S. active duty service …

PTSD, depression, and treatment outcomes: A latent profile analysis among active duty personnel in a residential PTSD program

Abstract: Depression frequently co-occurs with posttraumatic stress disorder (PTSD), including among active duty service members. However, symptom heterogeneity of this comorbidity …

Changes in guilt cognitions mediate the effect of trauma-informed guilt reduction therapy on PTSD and depression outcomes

Abstract: OBJECTIVE: Trauma-informed guilt reduction therapy (TrIGR), a six-session cognitive behavioral therapy targeting trauma-related guilt and distress, reduces guilt and …

Residual posttraumatic stress disorder and depression symptoms following a residential posttraumatic stress disorder treatment program for US active duty service members

Abstract: Objective: Even after the most effective posttraumatic stress disorder (PTSD) treatments, symptoms often persist. Understanding residual symptoms is particularly relevant …