• Author: Brent S. Rose
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Genomic risk model to implement precision prostate cancer screening in clinical care: The ProGRESS study

Abstract: Precision healthcare aims to tailor disease prevention and early detection to individual risk. Prostate cancer screening may benefit from genomics-informed approaches. We …

Prostate cancer incidence and outcomes among Vietnam Veterans receiving care in the Veterans Health Administration

Abstract: BACKGROUND: Agent Orange exposure (AOE) is considered a presumptive cause of prostate cancer (PCa) in the Veterans Affairs (VA) population; however, cohort studies …

Somatic tumor next-generation sequencing in US Veterans with metastatic prostate cancer

Abstract: IMPORTANCE: National guidelines recommend next-generation sequencing (NGS) of tumors in patients diagnosed with metastatic prostate cancer (mPCa) to identify potential …

Discovery of novel ancestry specific genes for androgens and hypogonadism in Million Veteran Program men

Abstract: Given the various roles of testosterone in men’s health, we conducted a multi-ancestral genetic analysis of total testosterone, free testosterone, SHBG, and …

Incidence of benign prostatic hyperplasia in testicular cancer survivors in the Veteran's affairs health system

Abstract: INTRODUCTION: Testosterone and prostatic inflammation have been postulated to influence the development of benign prostatic hyperplasia (BPH). Our study aims to evaluate …

Osteoporosis amongst testicular cancer survivors: Long term follow-up of the Veterans Affairs Health System

Abstract: INTRODUCTION: Testicular cancer (TC) is the most common malignancy among young males and is associated with cure rates over 95%. However, the long-term health …

Healthy lifestyle and prostate cancer risk in the Million Veteran Program

Abstract: Background: This study aims to assess the impact of healthy lifestyle on prostate cancer (PCa) risk in a diverse population. Methods: Data for 281,923 men from the …

Agent Orange exposure and prostate cancer risk in the million Veteran program

Abstract: Background: The US government considers veterans to have been exposed to Agent Orange if they served in Vietnam while the carcinogen was in use, and these veterans are …

The role of radical cystectomy in clinically node positive bladder cancer: A US Veterans Health Administration study

Abstract: Introduction: The role of local definitive therapy in addition to systemic treatment in clinically positive regional lymph node (cN + ) bladder cancer is yet to be …

Racial and Ethnic Disparities in Prostate Cancer Outcomes in the Veterans Affairs Health Care System

Abstract: Prostate cancer (PCa) disproportionately affects African American men, but research evaluating the extent of racial and ethnic disparities across the PCa continuum in …