• Author: Caroline M. Nievergelt
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A multi-ancestry meta genome-wide association study of migraine among Veterans: Associations with traumatic brain injury, depression, and post-traumatic stress disorder

Abstract: Migraine is a neurovascular disorder that poses a high burden to Veterans, who face a greater risk than sex-matched individuals in the general population. Genetic …

A prospective study of pre-trauma fear learning and extinction as risk factors for posttraumatic stress disorder

Abstract: Identifying risk for developing trauma-related disorders is a critical step in future prevention and intervention strategies. Impairments in inhibition of learned fear, …

Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts

Abstract: Background: Incorporating genomic data into risk prediction has become an increasingly popular approach for rapid identification of individuals most at risk for complex …

Migraine prevalence, environmental risk, and comorbidities in men and women Veterans

Abstract: IMPORTANCE: Migraine is a prevalent and debilitating condition that substantially impacts quality of life. Investigating migraine prevalence, associated comorbidities, …

Childhood unpredictability is associated with increased risk for long- and short-term depression and anhedonia symptoms following combat deployment

Abstract: High unpredictability has emerged as a dimension of early-life adversity that may contribute to a host of deleterious consequences later in life. Early-life …

Genome-wide association study of traumatic brain injury in US military veterans enrolled in the VA million veteran program

Abstract: Large-scale genetic studies of traumatic brain injury (TBI) are lacking; thus, our understanding of the influence of genetic factors on TBI risk and recovery is …

Pre-deployment threat learning predicts increased risk for post-deployment insomnia: Evidence from the Marine Resiliency Study

Abstract: Insomnia is a common and impairing consequence of military deployment, but little is known about pre-deployment risk factors for post-deployment insomnia. Abnormal threat …