• Author: Christopher T. Rentsch
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Associations between prior and current unhealthy alcohol use and liver morbidity risk and mortality among Veterans with a history of hepatitis C who have achieved sustained virological response

Abstract: The degree to which alcohol use is associated with the risk of all-cause mortality and hepatic decompensation after hepatitis C (HCV) diagnosis, treatment, and cure …

Concurrent alcohol use and the relative risk of community-acquired pneumonia associated with anticholinergic and non-anticholinergic neurocognitively active medication receipt: A national nested case–control study among US Veterans

Abstract: Purpose: Anticholinergic medications and alcohol each independently increase the risk of community-acquired pneumonia (CAP). Whether non-anticholinergic neurocognitively …

Association between herpes zoster and risk of incident fragility fractures in US Veterans: A matched cohort study

Abstract: Background: Herpes zoster (HZ) and fragility fractures typically affect older adults and present major burdens to healthcare systems. While HZ is associated with an …

Association between herpes zoster and risk of incident fragility fractures in US Veterans: A matched cohort study

Abstract: Background: Herpes zoster (HZ) and fragility fractures typically affect older adults and present major burdens to healthcare systems. While HZ is associated with an …

A Mendelian randomization study of alcohol use and cardiometabolic disease risk in a multi-ancestry population from the Million Veteran Program

Abstract: Background: Observational studies link moderate alcohol consumption to reduced risk of cardiometabolic diseases, including coronary heart disease (CHD) and type 2 …

Candidate genes from an FDA-approved algorithm fail to predict opioid use disorder risk in over 450,000 Veterans

Abstract: Importance: Recently, the Food and Drug Administration gave pre-marketing approval to algorithm based on its purported ability to identify genetic risk for opioid use …

Excess mortality in US veterans during the covid-19 pandemic: an individual-level cohort study

Abstract: Background: Most analyses of excess mortality during the COVID-19 pandemic have employed aggregate data. Individual-level data from the largest integrated healthcare …

Racial and Ethnic Bias in the Diagnosis of Alcohol Use Disorder in Veterans

Abstract: Studies show that racially and ethnically minoritized veterans have a higher prevalence of alcohol use disorder (AUD) than White veterans. The investigators examined …

Excess Mortality Among Patients in the Veterans Affairs Health System Compared With the Overall US Population During the First Year of the COVID-19 Pandemic

Abstract: During the first year of the COVID-19 pandemic, there was a substantial increase in the rate of death in the United States. It is unclear whether those who had access to …

Potentially inappropriate medication use by level of polypharmacy among US Veterans 49–64 and 65–70 years old

Abstract: Background: Potentially inappropriate medications (PIMs) are medications contra-indicated in particular circumstances. We sought to characterize PIMs by level of …