Abstract: BACKGROUND: Germline pathogenic variants can inform targeted therapy for metastatic prostate cancer (mPC), and improve cancer early detection and risk reduction for …
Abstract: Precision healthcare aims to tailor disease prevention and early detection to individual risk. Prostate cancer screening may benefit from genomics-informed approaches. We …
Abstract: Background: Black individuals have higher incidence and mortality rates of prostate cancer than White individuals, and existing literature on treatment sequencing …
Abstract:Hereditary transthyretin amyloidosis is caused by pathogenic variants in the TTR gene, resulting in abnormal TTR (transthyretin) that deposits in organs. The c.424G>A …
Abstract: IMPORTANCE: Pharmacogenetics can improve medication-related outcomes by optimizing efficacy and minimizing adverse effects. It is unknown whether the presence of …
Abstract: Given the various roles of testosterone in men’s health, we conducted a multi-ancestral genetic analysis of total testosterone, free testosterone, SHBG, and …