• Author: Michelle F. Dennis
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Whole exome sequencing analysis of suicidal thoughts and behaviors in a Veteran cohort implicates inflammatory pathways and genes previously associated with psychiatric and neurodegenerative diseases

Abstract: BACKGROUND: Suicide is a leading cause of death among younger veterans; however, the genetic basis of suicide remains largely unknown. While prior genome-wide association …

Accelerated epigenetic aging and prospective morbidity and mortality among U.S. Veterans

Abstract: BACKGROUND: Epigenetic aging measures have promise as surrogate health outcomes in randomized control trials and observational cohort studies. The value of these …

Multimodal smoking cessation treatment combining repetitive transcranial magnetic stimulation, cognitive behavioral therapy, and nicotine replacement in Veterans with posttraumatic stress disorder: A feasibility randomized controlled trial protocol

Abstract: Tobacco-related deaths remain the leading cause of preventable death in the United States. Veterans suffering from posttraumatic stress disorder (PTSD)-about 11% of those …

Demographic Characteristics and Epigenetic Biological Aging Among Post-9/11 Veterans: Associations of DunedinPACE with Sex, Race, and Age

Abstract: Measures of epigenetic aging derived from DNA methylation (DNAm) have enabled the assessment of biological aging in new populations and cohorts. In the present study, we …

High dimensional predictions of suicide risk in 4.2 million US Veterans using ensemble transfer learning

Abstract: We present an ensemble transfer learning method to predict suicide from Veterans Affairs (VA) electronic medical records (EMR). A diverse set of base models was trained …

Posttraumatic stress disorder, trauma, and accelerated biological aging among post-9/11 Veterans

Abstract: People who experience trauma and develop posttraumatic stress disorder (PTSD) are at increased risk for poor health. One mechanism that could explain this risk is …

Genome-wide DNA methylation analysis of cannabis use disorder in a Veteran cohort enriched for posttraumatic stress disorder

Abstract: Cannabis use has been increasing over the past decade, not only in the general US population, but particularly among military veterans. With this rise in use has come a …

Impact of traumatic life events and polygenic risk scores for major depression and posttraumatic stress disorder on Iraq/Afghanistan Veterans

Abstract: Traumatic experiences and genetic heritability are among the most widely acknowledged risk factors leading to the development of psychopathology; including posttraumatic …

Moral transgression during the Vietnam War: a path analysis of the psychological impact of veterans’ involvement in wartime atrocities

Abstract: Background and Objectives: Involvement in wartime combat often conveys a number of deleterious outcomes, including posttraumatic stress disorder (PTSD), depression, …