• Journal: Clinical Pharmacology & Therapeutics
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Association of pregabalin vs. duloxetine with cardiovascular events: A retrospective cohort study among US Veterans with chronic musculoskeletal pain

Abstract: Pregabalin and duloxetine are widely prescribed non-opioid medications for chronic musculoskeletal pain. Pregabalin may increase the risk of heart failure, and duloxetine …

CYP2C19 polymorphisms and clinical outcomes following percutaneous coronary intervention in the Million Veteran Program

Abstract: CYP2C19 loss-of-function (LOF) alleles decrease the antiplatelet effect of clopidogrel following percutaneous coronary intervention (PCI) in patients presenting with …

Association of pharmacogenomic phenotypes in CYP2D6, CYP2C9, CYP2C19, and CYP3A5 on polypharmacy in Veterans

Abstract: The Department of Veterans Affairs (VA) utilizes a pharmacogenomic (PGx) program that analyzes specific "pharmacogenes." This study evaluates the effect that …