Association of antidepressant serotonin transporter affinity with bleeding events in a Veteran population

Abstract: PURPOSE/BACKGROUND: Treatment-emergent bleeding is a well-known risk with serotonergic antidepressants. Studies assessing this risk based on varying serotonergic binding …

Leveraging COVID-19 to modernise depression care for VA primary care populations: Protocol for a sequential explanatory mixed method evaluation

Abstract: Background: The Veterans Health Administration (VA) integrated mental and physical health services to better detect and treat depression. Primary care nurses conduct …

Antidepressant medication prescription and incident cardiovascular disease in women Veterans

Abstract: Objective: Antidepressants are commonly prescribed, yet understanding of consequences for cardiovascular disease (CVD) risk is less well-developed. We examined …

Longitudinal Oral and Fecal Microbiome Alterations in Veterans With New Antidepressant Monotherapy for Major Depressive Disorder

Abstract: Major depressive disorder (MDD) is associated with a wide range of adverse outcomes. Though antidepressants are often implemented as first-line treatments for MDD, …

Exploring the prevalence of antidepressant medication discontinuation among pregnant veterans

Abstract: US female veterans have higher rates of mental health (MH) disorders compared to US civilian females and, consequently, are at risk for poor MH outcomes during pregnancy. …

Development of a model to predict combined antidepressant medication and psychotherapy treatment response for depression among veterans

Abstract: Although research shows that more depressed patients respond to combined antidepressants (ADM) and psychotherapy than either alone, many patients do not respond even to …