Preliminary insights into methylation patterns in Agent Orange exposed thyroid cancers: A pilot study

Abstract: During the Vietnam War, US military personnel were widely exposed to a tactical defoliant called Agent Orange, contaminated with a toxic endocrine-disrupting chemical, 2, …

A psychobiological approach to Gulf War Illness: Acute exercise & DNA methylation

Abstract:Background: Gulf War Illness (GWI) is a form of chronic multi-symptom illness characterized by medically unexplained and heterogenous symptoms (e.g., fatigue, pain, …

Association of PTSD symptom trajectories with accelerated pace of epigenetic aging in U.S. military Veterans

Abstract: Background: Mental disorders such as posttraumatic stress disorder (PTSD) are prevalent among U.S. military veterans. PTSD is often a chronic and disabling condition …

Accelerated epigenetic aging and prospective morbidity and mortality among U.S. Veterans

Abstract: BACKGROUND: Epigenetic aging measures have promise as surrogate health outcomes in randomized control trials and observational cohort studies. The value of these …

Comparing Veteran and nonveteran epigenetic aging in a representative sample of United States adults

Abstract:Introduction: Military service can significantly impact human health, with research showing that veterans experience higher mortality rates than the general population. …

Examining the epigenetic transmission of risk for chronic pain associated with paternal post-traumatic stress disorder: A focus on Veteran populations

Abstract: Chronic pain is a public health problem that significantly reduces quality of life. Although the aetiology is often unknown, recent evidence suggests that susceptibility …

Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts

Abstract: Background: Incorporating genomic data into risk prediction has become an increasingly popular approach for rapid identification of individuals most at risk for complex …

Demographic Characteristics and Epigenetic Biological Aging Among Post-9/11 Veterans: Associations of DunedinPACE with Sex, Race, and Age

Abstract: Measures of epigenetic aging derived from DNA methylation (DNAm) have enabled the assessment of biological aging in new populations and cohorts. In the present study, we …

Study protocol: Identifying transcriptional regulatory alterations of chronic effects of blast and disturbed sleep in United States Veterans

Abstract: Injury related to blast exposure dramatically rose during post-911 era military conflicts in Iraq and Afghanistan. Mild traumatic brain injury (mTBI) is among the most …

Prominent genetic variants and epigenetic changes in post-traumatic stress disorder among combat Veterans

Abstract: Post-traumatic stress disorder (PTSD) is one of the most widespread and disabling psychiatric disorders among combat veterans. Substantial interindividual variability in …

Genome-wide DNA methylation analysis in female Veterans with military sexual trauma and comorbid PTSD/MDD

Abstract: BACKGROUND: Military sexual trauma (MST) is a prevalent issue within the U.S. military. Victims are more likely to develop comorbid diseases such as posttraumatic stress …

Differential methylation of linoleic acid pathway genes is associated with PTSD symptoms - a longitudinal study with Burundian soldiers returning from a war zone

Abstract: Soldiers may be exposed to traumatic stress during combat deployment and thus are at risk for developing posttraumatic stress disorder (PTSD). Genetic and epigenetic …