Hyperarousal as a key predictor in longitudinal trajectories of insomnia symptoms up to 10 years post-deployment in military personnel

Abstract: STUDY OBJECTIVES: Insomnia is a common sleeping disorder in military personnel and is linked to the development and maintenance of other mental health symptoms. How …

Associations of chronic pain and PTSD factors among military personnel: An exploration of the mutual maintenance model

Abstract: Introduction: Chronic pain is common among Canadian Armed Forces (CAF) service members and Veterans. This has prompted investigators to develop theoretical models that …

A phase 3, randomized, placebo-controlled, trial to evaluate the efficacy and safety of bedtime sublingual cyclobenzaprine (TNX-102 SL) in military-related posttraumatic stress disorder

Abstract: Sleep disturbances in posttraumatic stress disorder (PTSD) are a potential target for improving PTSD severity with pharmacotherapy. TNX-102 SL is a bedtime sublingual …

Suicidal ideation and attempts and hyperarousal in military personnel and Veterans: Network analysis reveals roles of anxiety sensitivity and insomnia

Abstract: OBJECTIVE: Suicidal thoughts and behaviors (STBs) are a serious public health problem in the United States and of particular concern among active-duty service members and …

Evidence for locus coeruleus-norepinephrine system abnormality in Military PTSD revealed by neuromelanin-sensitive MRI

Abstract: BACKGROUND: The complex neurobiology of post-traumatic stress disorder (PTSD) calls for the characterization of specific disruptions in brain functions that require …

Differences in the phenotypic expression of posttraumatic stress disorder symptoms in US military Veterans with and without clinical insomnia

Abstract: STUDY OBJECTIVES: The goal of this study was to examine the phenotypic expression of posttraumatic stress disorder (PTSD) symptoms in veterans with probable PTSD and …

Preliminary evidence of transcutaneous vagus nerve stimulation effects on sleep in Veterans with post-traumatic stress disorder

Abstract: Sleep problems are common among veterans with post-traumatic stress disorder and closely associated with hyperarousal symptoms. Transcutaneous vagus nerve stimulation …

Hyperarousal symptoms linger after successful PTSD treatment in active duty military

Abstract: Objective: Evidence-based psychotherapies are efficacious at reducing posttraumatic stress disorder (PTSD) symptoms, but military and veteran samples improve less than …

123. The Late Positive Potential Response to Olfactory Stimuli in Combat Veterans with Posttraumatic Stress Disorder

Abstract: Background: A potential treatment moderator for PTSD is severity of emotional dysregulation. The late positive potential (LPP) amplitude from EEG has been used to assess …