Abstract: Abstract: Background Health care literacy has been linked to patient health and outcomes. Health literacy tests (HLTs) are hampered by administration time and specialty specific utility. The 75-word Rapid Estimate of Adult Literacy in Vascular Surgery (REAL_VS) was developed from the more extensive but less specific Rapid Estimate of Adult Literacy in Medicine (REALM) to assess vascular health literacy. Objectives We aim to validate the use of the REAL_VS in a veteran population, using the REALM as the gold standard. Methods Vascular surgery patients were examined utilizing these HLTs at a level 1A Veterans Affairs (VA) hospital. Sociodemographic information was collected. Spearman’s rank correlations (⍴) and area under the receiver operating characteristics (ROC) curves with corresponding 95% confidence intervals (CI) were calculated for a sixth-grade educational threshold (6-ET). Results One hundred and seventy-seven English-speaking patients (mean age = 69 ± 11.9 years) were enrolled. REAL_VS scores were highly correlated with REALM scores (⍴=0.86 and 0.77; p<0.001, respectively). A REAL_VS score of 54 corresponded to the established REALM 6-ET score of 44 with a sensitivity and specificity of 0.875 and 0.96, respectively. The AUC for the REAL_VS predicting less than 6-ET was 0.985 with CI=0.97-1.00. Conclusions Our study demonstrates the REAL_VS may be used to accurately assess vascular health literacy in veteran patients undergoing vascular surgery consultation and may aid in assessing specialty specific health literacy.