Abstract: OBJECTIVE: This study aims to assess the regression rate of basal cell carcinoma (BCC) in excision specimens following diagnostic biopsies obtained from patients in a veterans affairs facility. METHODS: A retrospective review of biopsy-proven BCC excision cases was conducted. All included biopsy and corresponding excision reports were reviewed to determine the margin status of specimens. Proportion of residual carcinoma cases and regression rate of the tumor were determined. RESULTS: Regression rate of BCC was estimated to be 47%. The most prevalent subtype was nodular BCC (46%), and the most prevalent location was the head. Tumors located on the trunk and upper extremities were more likely to regress, and those on the head were less likely to regress (p<0.05). Punch biopsy technique was associated with significantly lower regression rate (p<0.01). The time interval between the biopsy and excision and age were not significantly different between regressed and non-regressed tumors. Neither of sexes and neither of tumor subtypes had significantly different regression rates as compared to the general study population. LIMITATIONS: The limitation of our study is that the data may not be generalizable due to our unique study population. CONCLUSION: BCC is a tumor with the potential to regress. However, definitive management resides in complete surgical excision, which will most likely remain the mainstay of treatment in the near future.