Posttraumatic stress disorder symptoms and suicide ideation, attempt, and risk among active-duty service members and Veterans: A systematic review with three meta-analyses of associations and moderators

Abstract: Posttraumatic stress disorder (PTSD) is an established risk factor for suicidality in service members and veterans (SM/Vs). However, no meta-analysis has examined associations between PTSD symptom severity and suicidality in SM/Vs or moderators of these relationships. Three meta-analyses examined cross-sectional correlations between PTSD symptoms and suicide ideation, attempt, and risk. Seven databases were searched four times, most recently in June 2025. Eligible reports had to include adult SM/Vs, be written in English, be published in or after 1980, assess PTSD symptoms, and include a validated measure of suicidal ideation, attempts, or risk (or single item of attempts). We included 87 ideation effect sizes representing 82,318 SM/Vs, 74 attempt effect sizes representing 104,952 SM/Vs, and 45 risk effect sizes representing 38,927 SM/Vs. Correlated-and-hierarchical effects models with robust variance estimation revealed significant summary correlations for ideation (rz = 0.29; 95 % PI [0.02, 0.57]), attempt (rz = 0.16; 95 % PI [0.003, 0.32]), and risk (rz = 0.40; 95 % PI [0.08, 0.72]), all with statistically significant heterogeneity. Among 19 moderators tested, veteran status (v. active-duty) significantly strengthened the correlation with suicidal ideation (b = 0.12, se = 0.04, t(34.03) = 2.91, p = .006) and suicide attempt (b = 0.08, se = 0.03, t(19.83) = 2.44, p = .024). Partnered status significantly strengthened the correlation with suicide risk (b = 0.01, se = 0.00, t(8.77) = 4.62, p = .001). Findings highlight who might be at greater risk for suicide and underscore the potential benefits of treating PTSD symptoms for suicide prevention in SM/Vs.

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