• Author: Amy C. Justice
Clear all

Candidate genes from an FDA-approved algorithm fail to predict opioid use disorder risk in over 450,000 Veterans

Abstract: Importance: Recently, the Food and Drug Administration gave pre-marketing approval to algorithm based on its purported ability to identify genetic risk for opioid use …

Development and validation of case-finding algorithms to identify pancreatic cancer in the Veterans Health Administration

Abstract: BACKGROUND: Survival in pancreatic ductal adenocarcinoma (PDAC) remains poor due to late diagnosis. Electronic Health Records (EHRs) can be used to study this rare …

A multi-ancestry genetic study of pain intensity in 598,339 Veterans

Abstract: Chronic pain is a common problem, with more than one-fifth of adult Americans reporting pain daily or on most days. It adversely affects the quality of life and imposes …

High dimensional predictions of suicide risk in 4.2 million US Veterans using ensemble transfer learning

Abstract: We present an ensemble transfer learning method to predict suicide from Veterans Affairs (VA) electronic medical records (EMR). A diverse set of base models was trained …

Hypertension control during the coronavirus disease 2019 pandemic: a cohort study among U.S. Veterans

Abstract: DESIGN: Retrospective cohort study. OBJECTIVE: We sought to examine whether disruptions in follow-up intervals contributed to hypertension control. BACKGROUND: …

Excess mortality in US veterans during the covid-19 pandemic: an individual-level cohort study

Abstract: Background: Most analyses of excess mortality during the COVID-19 pandemic have employed aggregate data. Individual-level data from the largest integrated healthcare …

Risk factors for suicide among veterans living with and without HIV: a nested case-control study

Abstract: The rate of suicide among people with HIV (PWH) remains elevated compared to the general population. The aim of the study was to examine the association between a broad …

Multi-trait genome-wide association analyses leveraging alcohol use disorder findings identify novel loci for smoking behaviors in the Million Veteran Program

Abstract: Smoking behaviors and alcohol use disorder (AUD), both moderately heritable traits, commonly co-occur in the general population. Single-trait genome-wide association …

Racial and Ethnic Bias in the Diagnosis of Alcohol Use Disorder in Veterans

Abstract: Studies show that racially and ethnically minoritized veterans have a higher prevalence of alcohol use disorder (AUD) than White veterans. The investigators examined …

Excess Mortality Among Patients in the Veterans Affairs Health System Compared With the Overall US Population During the First Year of the COVID-19 Pandemic

Abstract: During the first year of the COVID-19 pandemic, there was a substantial increase in the rate of death in the United States. It is unclear whether those who had access to …

Treating Hepatitis C in Individuals With Previous Incarceration: The Veterans Health Administration, 2012–2019

Abstract: To determine whether the Veterans Health Administration's (VHA) hepatitis C (HCV) treatment campaign reached marginalized populations, we compared HCV care by previous …

Potentially inappropriate medication use by level of polypharmacy among US Veterans 49–64 and 65–70 years old

Abstract: Background: Potentially inappropriate medications (PIMs) are medications contra-indicated in particular circumstances. We sought to characterize PIMs by level of …