• Author: Ariela R. Orkaby
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Measuring frailty using self-report or automated tools to identify risk of cardiovascular events and mortality: The Million Veteran Program

Abstract: Background: Frailty, a syndrome of physiologic vulnerability, increases cardiovascular disease (CVD) risk. Whether in person or automated frailty tools are ideal for …

The frailty trajectory's additional edge over the frailty index: Retrospective cohort study of Veterans with heart failure

Abstract: Individuals with heart failure (HF) have a high burden of health care utilization, costs, and morbidity in the year following hospitalization for an acute HF …

Incidence and prognostic significance of newly-diagnosed atrial fibrillation among older U.S. Veterans hospitalized with COVID-19

Abstract: Most prior studies on the prognostic significance of newly-diagnosed atrial fibrillation (AF) in COVID-19 did not differentiate newly-diagnosed AF from pre-existing AF. …

New statin use, mortality and first cardiovascular events in older US Veterans by frailty status

Abstract: BACKGROUND: Statins are part of long-term medical regimens for many older adults. Whether frailty modifies the protective relationship between statins, mortality, and …

Statins, mortality, and major adverse cardiovascular events among US Veterans with chronic kidney disease

Abstract: IMPORTANCE: There are limited data for the utility of statins for primary prevention of atherosclerotic cardiovascular disease (ASCVD) and death in adults with chronic …

Serum cholesterol and impact of age on coronary heart disease death in more than 4 million veterans

Abstract: Background: The lipid hypothesis postulates that lower blood cholesterol is associated with reduced coronary heart disease (CHD) risk, which has been challenged by …

Construct validity of the electronic Veterans Affairs Frailty Index against clinician frailty assessment

Abstract: Background: Electronic frailty indices (eFIs) can expand measurement of frailty in research and practice and have demonstrated predictive validity in associations with …

Comparison of claims-based frailty indices in u.s. veterans 65 and older for prediction of long-term institutionalization and mortality

Abstract: Background: Frailty is increasingly recognized as a useful measure of vulnerability in older adults. Multiple claims-based frailty indices (CFIs) can readily identify …

Predictive value of ASCVD risk score for mortality and major adverse cardiovascular events in the year following a COVID-19 infection among US Veterans

Abstract: Morbidity and mortality following COVID-19 infection may be influenced by baseline atherosclerotic cardiovascular disease (ASCVD) risk, yet limited data are available to …

Preoperative frailty and adverse outcomes following coronary artery bypass grafting surgery in US veterans

Abstract: Contemporary guidelines emphasize the value of incorporating frailty into clinical decision-making regarding revascularization strategies for coronary artery disease. …

The Burden of Frailty Among U.S. Veterans and Its Association With Mortality, 2002–2012

Abstract: Background: Frailty is a key determinant of clinical outcomes. We sought to describe frailty among U.S. Veterans and its association with mortality. Methods: Nationwide …