• Author: Jason L. Vassy
Clear all

Genomic risk model to implement precision prostate cancer screening in clinical care: The ProGRESS study

Abstract: Precision healthcare aims to tailor disease prevention and early detection to individual risk. Prostate cancer screening may benefit from genomics-informed approaches. We …

CYP2C19 polymorphisms and clinical outcomes following percutaneous coronary intervention in the Million Veteran Program

Abstract: CYP2C19 loss-of-function (LOF) alleles decrease the antiplatelet effect of clopidogrel following percutaneous coronary intervention (PCI) in patients presenting with …

Veteran participation in the All of Us Research Program: Applying an intersectionality lens to evaluate participant diversity

Abstract: BACKGROUND: Many segments of the population are underrepresented in biomedical research (UBR). Lack of diversity in health research limits understanding of individual and …

Healthy lifestyle and prostate cancer risk in the Million Veteran Program

Abstract: Background: This study aims to assess the impact of healthy lifestyle on prostate cancer (PCa) risk in a diverse population. Methods: Data for 281,923 men from the …

Design and pilot results from Million Veteran Program return of actionable genetic results (MVP-ROAR) study

Abstract: Background: As a mega-biobank linked to a national healthcare system, the Million Veteran Program (MVP) can directly improve the health care of participants. To determine …

Development and utility of a clinical research informatics application for participant recruitment and workflow management for a return of results pilot trial in familial hypercholesterolemia in the Million Veteran Program

Abstract: OBJECTIVE: The development of clinical research informatics tools and workflow processes associated with re-engaging biobank participants has become necessary as genomic …

Serum cholesterol and impact of age on coronary heart disease death in more than 4 million veterans

Abstract: Background: The lipid hypothesis postulates that lower blood cholesterol is associated with reduced coronary heart disease (CHD) risk, which has been challenged by …