• Author: Leland E. Hull
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Risk of systemic manifestations in homozygous carriers of the transthyretinV142I variant: A Million Veteran Program analysis

Abstract:Hereditary transthyretin amyloidosis is caused by pathogenic variants in the TTR gene, resulting in abnormal TTR (transthyretin) that deposits in organs. The c.424G>A …

Drug-drug-gene interaction risk among opioid users in the U.S. Department of Veterans Affairs

Abstract: Response to analgesic therapy is influenced by several factors including genetics and drug-drug interactions. Pharmacogenetic (PGx) variants in the CYP2D6 gene modify …