Abstract:Epidemiologic studies suggest an association between Parkinson's disease (PD) and melanoma, although mechanisms remain unclear. Shared immune dysregulation, oxidative …
Abstract:The Veterans Health Administration is the largest integrated health care system in the United States, providing care to over 9 million individuals annually.1 Prior studies …
Abstract: IMPORTANCE: Pharmacogenetics can improve medication-related outcomes by optimizing efficacy and minimizing adverse effects. It is unknown whether the presence of …
Abstract: IMPORTANCE: The US Veterans Health Administration (VHA) provides comprehensive medical care for enrolled veterans. Differences in melanoma diagnosis, associated with …
Abstract: Venetoclax-based therapies combined with either a DNA methyltransferase inhibitor or low-dose cytarabine have become the standard frontline treatment for older or unfit …
Abstract: Rationale: Older adults make up the majority of patients with advanced non-small cell lung cancer (NSCLC) and often carry multiple other comorbidities (multimorbidity) …
Abstract: Introduction: The use of antidepressants in major depressive disorder (MDD) has been reported to influence long-term risk of Alzheimer's disease (AD) and AD-related …
Abstract: Persons diagnosed with schizophrenia (SCZ) or bipolar I disorder (BPI) are at high risk for self-injurious behavior, suicidal ideation, and suicidal behaviors (SB). …
Abstract: Importance: With SARS-CoV-2 transforming into an endemic disease and with antiviral treatments available, it is important to establish which patients remain at risk of …
Abstract: BACKGROUND: Patients taking immune-suppressive drugs are at increased risk of severe coronavirus disease 2019 (COVID-19), not fully ameliorated by vaccination. We …
Abstract: IMPORTANCE: Many psychiatric outcomes share a common etiologic pathway reflecting behavioral disinhibition, generally referred to as externalizing (EXT) disorders. Recent …
Abstract: BACKGROUND: Comprehensive analysis of brain tumor incidence and survival in the Veteran population has been lacking. METHODS: Veteran data were obtained from the Veterans …