Abstract:Hereditary transthyretin amyloidosis is caused by pathogenic variants in the TTR gene, resulting in abnormal TTR (transthyretin) that deposits in organs. The c.424G>A …
Abstract:Objective: The prevalence of moderate to severe asymptomatic carotid stenosis (i.e., atherosclerotic narrowing of the extracranial carotid arteries) is generally ∼6% and …
Abstract: IMPORTANCE: Pharmacogenetics can improve medication-related outcomes by optimizing efficacy and minimizing adverse effects. It is unknown whether the presence of …
Abstract: CYP2C19 loss-of-function (LOF) alleles decrease the antiplatelet effect of clopidogrel following percutaneous coronary intervention (PCI) in patients presenting with …
Abstract: Background: Patients who undergo below-knee surgical amputation (BKA) are at risk of postoperative venous thromboembolism (VTE). Limited prior studies quantified the rate …
Abstract: Background: US military Veterans account for a disproportionate share of adults experiencing homelessness. Individuals experiencing homelessness and unstable housing …