• Author: Scott P. Orr
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A late-life neurogenetic signature of exposure to combat stress - a monozygotic discordant twin study

Abstract: Animal models suggest that experiencing high-stress levels induces changes in amygdalar circuitry and gene expression. In humans, combat exposure has been shown to alter …

Augmenting treatment efficiency in exposure therapy for PTSD: a randomized double-blind placebo-controlled trial of yohimbine HCl

Abstract: The alpha-2 adrenergic receptor antagonist, yohimbine, can facilitate fear extinction in animals and humans. One potential mechanism is increased noradrenergic activity …

Heart rate reactivity to trauma-related imagery as a measure of PTSD symptom severity : Examining a new cohort of Veterans

Abstract: For over three decades, there has been considerable research documenting increased physiological reactivity to trauma-related stimuli as a characteristic feature of …