• Journal: Journal of the American Heart Association
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Insomnia, sleep apnea, and incidence of hypertension and cardiovascular disease among men and women US Veterans

Abstract: BACKGROUND: Comorbid insomnia and obstructive sleep apnea (COMISA) is associated with cardiovascular disease (CVD) in older adults. The associations of COMISA with …

Risk of systemic manifestations in homozygous carriers of the transthyretinV142I variant: A Million Veteran Program analysis

Abstract:Hereditary transthyretin amyloidosis is caused by pathogenic variants in the TTR gene, resulting in abnormal TTR (transthyretin) that deposits in organs. The c.424G>A …

Management and outcomes of patients undergoing cardiovascular evaluation across health care systems: Comparison of community care and integrated Veterans Affairs health care

Abstract: Background: The Veterans Affairs (VA) Healthcare System maintains the largest integrated health system in the United States but also supports fee‐for‐service …

Long-term outcomes of peripheral artery disease in Veterans: analysis of the peripheral artery disease long-term survival study (PEARLS)

Abstract: Background: Contemporary research in peripheral artery disease (PAD) remains limited due to lack of a national registry and low accuracy of diagnosis codes to identify …

Dietary cholesterol and myocardial infarction in the Million Veteran Program

Abstract: Background: Coronary artery disease is a leading cause of morbidity and mortality in the United States. Coronary artery disease can lead to major complications including …

Variation in hypertension control by race and ethnicity, and geography in US Veterans

Abstract: Background: Hypertension control and related cardiovascular outcomes among Americans remain suboptimal, and differ by race, ethnicity, and geography. Healthcare access is …

Pathways from socioeconomic factors to major cardiovascular events among postmenopausal Veteran and nonveteran women: Findings from the Women's Health Initiative

Abstract: Background: Cardiovascular disease (CVD) remains a leading cause of death for women in the United States, with veterans being at potentially higher risk than their …

Prevalent atherosclerotic cardiovascular disease among Veterans by sexual orientation

Abstract: Background: Seven million lesbian, gay, and bisexual (LGB) adults will be aged >50?years by 2030; assessing and addressing their risk for cardiovascular disease is …

Trends in initial antihypertensive medication prescribing among >2.8 million Veterans newly diagnosed with hypertension, 2000 to 2019

Abstract: Background: Among patients diagnosed with high blood pressure (BP), initial dual therapy has been recommended for patients with high pretreatment systolic BP …

Racial and ethnic differences in adoption of mitral valve transcatheter edge-to-edge repair over a decade in the National Veterans Affairs Healthcare System

Abstract: Mitral valve transcatheter edge-to-edge repair (mTEER) has proven to be a valuable treatment for mitral regurgitation (MR), yet racial and ethnic disparities in its …

Measuring frailty using self-report or automated tools to identify risk of cardiovascular events and mortality: The Million Veteran Program

Abstract: Background: Frailty, a syndrome of physiologic vulnerability, increases cardiovascular disease (CVD) risk. Whether in person or automated frailty tools are ideal for …

Spironolactone reduces the risk of death in Veterans with heart failure with preserved ejection fraction

Abstract: Background: Heart failure with preserved ejection fraction (HFpEF) is a complex syndrome increasing in prevalence and affecting millions worldwide but with limited …