Time to dementia diagnosis among Veterans with comorbid insomnia and depressive episodes

Abstract: Background: Older adults with heart failure are at elevated risk of Alzheimer's disease and related dementias (AD/ADRD). Research suggests that insomnia and depressive …

Understanding racial disparities in dementia prevalence among Veterans

Abstract: Background: Black and Hispanic older adults have greater incidence of Alzheimer's disease and related dementias relative to White adults, but factors underlying these …

Is the risk of Alzheimer's disease and related dementias among U.S. Veterans influenced by the intersectionality of housing status, HIV/AIDS, hepatitis C, and psychiatric disorders?

Abstract: Background: Homelessness and housing instability disproportionately affect U.S. veterans with psychiatric disorders, HIV/AIDS, hepatitis C, and Alzheimer's Disease and …

Antidepressant exposure and long-term dementia risk in a nationwide retrospective study on US Veterans with midlife major depressive disorder

Abstract: Introduction: The use of antidepressants in major depressive disorder (MDD) has been reported to influence long-term risk of Alzheimer's disease (AD) and AD-related …

The Role of Mental Health Conditions in Early Detection and Treatment of Veterans With Alzheimer’s Dementia

Abstract: Introduction: The benefits of early detection of Alzheimer's disease (AD) have become increasingly recognized. Veterans with mental health conditions (MHCs) may be less …

Inviting Veterans into enrollment in Alzheimer's disease research centers (INVITE-ADRC): An NIA and VA-sponsored initiative to increase Veteran participation in aging and dementia research

Abstract: INTRODUCTION: Older military veterans often present with unique and complex risk factors for Alzheimer's disease (AD) and related dementias. Increasing veteran …

Predicting 5-year dementia conversion in Veterans with mild cognitive impairment

Abstract: INTRODUCTION: Identifying mild cognitive impairment (MCI) patients at risk for dementia could facilitate early interventions. Using electronic health records (EHRs), we …

Identifying Alzheimer's disease and related disorders via diagnostic codes in Veterans with heart failure

Abstract: Cognitive impairment due to Alzheimer's disease and related disorders (ADRD) threatens self-management ability when co-occurring with heart failure. ADRD also increases …

Risk of dementia among Veterans experiencing homelessness and housing instability

Abstract: BACKGROUND: In the United States, nearly 85,000 Veterans experienced homelessness during 2020, and thousands more are experiencing housing instability, representing a …

Association between military service and Alzheimer's disease neuropathology at autopsy

Abstract: INTRODUCTION: Anti-amyloid therapies are at the forefront of efforts to treat Alzheimer's disease (AD). Identifying amyloid risk factors may aid screening and …

Pimavanserin 34 mg at bedtime for the treatment of insomnia in 6 Veterans with posttraumatic stress disorder

Abstract: Insomnia is the most common and refractory complaint in Veterans with posttraumatic stress disorder (PTSD). This open-label pilot study of pimavanserin describes the …

Rule-based identification of individuals with mild cognitive impairment or Alzheimer's disease using clinical notes from the United States Veterans Affairs healthcare system

Abstract: BACKGROUND: Early identification of individuals with mild cognitive impairment (MCI) and Alzheimer's disease (AD) is a clinical and research imperative. Use of diagnostic …