Interactive effects of post-traumatic stress disorder symptom severity and hypertension on cognitive dispersion in older Vietnam-era Veterans with history of post-traumatic stress disorder

Abstract: Objective: Post-traumatic stress disorder (PTSD) and hypertension are highly prevalent among Veterans. Cognitive dispersion, indicating within-person variability across …

Amyloid-β and tau deposition in traumatic brain injury: A study of Vietnam War Veterans

Abstract: Traumatic brain injury is widely viewed as a risk factor for dementia, but the biological mechanisms underlying this association are still unclear. In previous studies, …

Evaluating disparity of subjective cognitive decline between male Veterans and non-Veterans in the United States using propensity score matching estimation: A behavioral risk factor surveillance system survey cross-sectional study

Abstract: Subjective cognitive decline (SCD) is one of the most important early onset symptoms of Alzheimer's Disease. Previous studies consistently reported that SCD is associated …

PTSD moderates the association between subjective cognitive decline and Alzheimer’s disease biomarkers in older Veterans

Abstract: Objectives: Post-traumatic stress disorder (PTSD) and subjective cognitive decline (SCD) are independent risk factors for Alzheimer’s disease (AD) and dementia, but the …

Associations of post-traumatic stress disorder and objective subtle cognitive difficulties in cognitively unimpaired older Veterans

Abstract: Introduction: Psychiatric conditions such as post-traumatic stress disorder (PTSD) and depression have a two-fold increased dementia risk in Veterans. Prior work has …

Cognition and Amyloid-β in Older Veterans: Characterization and Longitudinal Outcomes of Data-Derived Phenotypes

Abstract: Background: Within older Veterans, multiple factors may contribute to cognitive difficulties. Beyond Alzheimer’s disease (AD), psychiatric (e.g., PTSD) and health …

Agent Orange herbicidal toxin-initiation of Alzheimer-type neurodegeneration

Abstract: BACKGROUND: Agent Orange (AO) is a Vietnam War-era herbicide that contains a 1 : 1 ratio of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic …

Alzheimer's disease stage transitions among United States Veterans

Abstract: BACKGROUND: Alzheimer's disease (AD) and related dementias are progressive neurological disorders with stage-specific clinical features and challenges. An important …

Type 2 diabetes moderates the association between amyloid and 1-year change in everyday functioning in older Veterans

Abstract: BACKGROUND: Type 2 diabetes mellitus (T2DM) affects ∼25% of Veterans, a prevalence rate double that of the general population. T2DM is associated with greater dementia …

Cognitive function among military veterans with STEM occupations

Abstract: There is limited research on the relationship between science, technology, engineering, and mathematics (STEM) occupational history and cognitive function in later life, …