Physiological markers of trauma‐related nightmares among military personnel suffering from PTSD: A multicenter home‐recording study

Abstract:Aim: Despite being one of the most disabling symptoms of post-traumatic stress disorder (PTSD)—disrupting sleep continuity, reinforcing hyperarousal, and worsening …

Evaluating sex differences in biomarkers of chronic pain among active-duty personnel: An exploratory analysis of a pragmatic clinical trial with a SMART design

Abstract: Chronic pain affects approximately one-third of active-duty service members (ADSMs), yet effective treatment remains challenging. Salivary cortisol and urinary …

Abnormal serum albumin, alanine aminotransferase, and blood urea nitrogen are associated with higher risks for mechanical ventilation and in-hospital mortality in COVID-19 positive US Veterans

Abstract: BACKGROUND: Since the first reported case of Coronavirus Disease 2019 (COVID-19), clinicians and scientists have been challenged to contrive ideal prevention, detection, …

Urine metabolites as indicators of chronic pain and related symptoms in active-duty service members: A secondary data analysis of a pragmatic clinical trial with SMART design

Abstract: BACKGROUND: Chronic pain is a major cause of distress and disability, and biomarkers may aid in the assessment and treatment of it. Urine metabolites may be valuable …

Association of Alzheimer's disease genetic risk with age-dependent changes in plasma amyloid-β(42:40) in Veterans

Abstract: BackgroundIdentifying biomarkers of Alzheimer's disease (AD) is critical for early diagnosis and AD risk assessment.ObjectiveWe examined the hypothesis that the plasma …

Poor long-term outcomes and abnormal neurodegeneration biomarkers after military traumatic brain injury: The armed services trauma rehabilitation outcome study

Abstract: Background: Traumatic brain injury (TBI) is common in military campaigns and is a risk factor for dementia. ArmeD SerVices TrAuma and RehabilitatioN OutComE-TBI …

Biomarkers of long-term consequences of traumatic brain injuries sustained during military service

Abstract: This study investigates the long-term neuropsychiatric impacts of combat-associated traumatic brain injuries (TBI) in British veterans, using data from the ADVANCE-TBI …

Staging model of PTSD: A strategy for the implementation of precision medicine in military settings

Abstract: Biomarkers have been of considerable interest in military medicine as a strategy to identify objective measures of resilience in the context of the cumulative trauma …

Novel characterization of endogenous transient receptor potential melastatin 3 ion channels from Gulf War Illness participants

Abstract: Gulf War Illness (GWI) is a chronic condition characterized by multisystem symptoms that still affect up to one-third of veterans who engaged in combat in the Gulf War …

Comprehensive examination of resting state fMRI connectomics yields new insights into brain function deficits in Gulf War illness after accounting for heterogeneity in brain impairment across the ill Veteran population

Abstract: An estimated 200,000 veterans (up to 32% of those deployed) of the 1991 Gulf War (GW) suffer from GW illness (GWI), an incompletely understood chronic medical condition, …

Perivascular space burden and cerebrospinal fluid biomarkers in U.S. Veterans with blast-related mild traumatic brain injury

Abstract: Blast-related mild traumatic brain injury (mTBI) is recognized as the "signature injury" of the Iraq and Afghanistan wars. mTBI, sleep disruption, and neuroinflammation …

A cross-sectional study of correlations among blood-based biomarkers for intestinal permeability: a pilot study of United States Veterans with posttraumatic stress disorder symptoms

Abstract: While many studies of intestinal permeability (IP) are focused on those with gastrointestinal (GI) disorders, there is a rising trend to analyze IP among individuals with …