A psychobiological approach to Gulf War Illness: Acute exercise & DNA methylation

Abstract:Background: Gulf War Illness (GWI) is a form of chronic multi-symptom illness characterized by medically unexplained and heterogenous symptoms (e.g., fatigue, pain, …

Developmental timing of index trauma exposure and accelerated epigenetic aging in United States military Veterans

Abstract: Trauma exposure has been linked to accelerated GrimAge, an epigenetic biomarker of premature morbidity and mortality. Building on this evidence, the present study …

Developmental timing of index trauma exposure and accelerated epigenetic aging in United States military Veterans

Abstract: Trauma exposure has been linked to accelerated GrimAge, an epigenetic biomarker of premature morbidity and mortality. Building on this evidence, the present study …

Genetic and epigenetic analysis of plasma glial fibrillary acidic protein (GFAP) levels in PTSD

Abstract: Glial fibrillary acidic protein (GFAP) is an astrocytic marker that can be assessed in blood using single molecule array technology. Recent studies suggest that …

Comparing Veteran and nonveteran epigenetic aging in a representative sample of United States adults

Abstract:Introduction: Military service can significantly impact human health, with research showing that veterans experience higher mortality rates than the general population. …

Examining the epigenetic transmission of risk for chronic pain associated with paternal post-traumatic stress disorder: A focus on veteran populations

Abstract: Chronic pain is a public health problem that significantly reduces quality of life. Although the aetiology is often unknown, recent evidence suggests that susceptibility …

"Holy Cow, Where Do I Sign Up?" Attitudes of Military Veterans Toward Epigenomic Biomarker Toxic Exposure Testing

Abstract: Background: With the signing of the PACT Act in 2022, there is great interest and investment in studying toxic exposures encountered during military service. One way to …

Genome-wide DNA methylation analysis in female Veterans with military sexual trauma and comorbid PTSD/MDD

Abstract: BACKGROUND: Military sexual trauma (MST) is a prevalent issue within the U.S. military. Victims are more likely to develop comorbid diseases such as posttraumatic stress …

Genome-wide DNA methylation analysis of cannabis use disorder in a Veteran cohort enriched for posttraumatic stress disorder

Abstract: Cannabis use has been increasing over the past decade, not only in the general US population, but particularly among military veterans. With this rise in use has come a …

Ketamine produces antidepressant effects by inhibiting histone deacetylases and upregulating hippocampal BDNF levels in a DFP-based rat model of Gulf War Illness

Abstract: Approximately one-third of Gulf War veterans suffer from Gulf War Illness (GWI), which encompass mood disorders and depressive symptoms. Deployment-related exposure to …

Outdoor and Adventurous Activities in Supporting Wounded, Injured and Sick Military Personnel and Veterans

Summary: Advances in neuroscience and epigenetics within the field of trauma research and practice have progressed rapidly over the last two decades. Yet, a therapeutic practice …