Combining machine learning and comparative effectiveness methodology to study primary care pharmacotherapy pathways for Veterans with depression

Abstract: OBJECTIVES: To demonstrate an innovative method combining machine learning with comparative effectiveness research techniques and to investigate a hitherto unstudied …

Investigating amygdala nuclei volumes in military personnel with post-traumatic stress disorder, major depressive disorder, and adjustment disorder: A retrospective cross-sectional study using clinical routine data

Abstract: Background: Post-traumatic Stress Disorder (PTSD), Major Depressive Disorder (MDD), and Adjustment Disorder (AdjD) are highly prevalent among military personnel, often …

Predictors of dropout from transcranial magnetic stimulation for treatment resistant depression

Abstract: Clinical transcranial magnetic stimulation (TMS) is a well-established therapeutic intervention for treatment resistant depression and related comorbidities, yet standard …

Discontinuation of mental health treatment among Canadian military personnel

Abstract: Introduction: Mental health problems are prevalent among Canadian Armed Forces (CAF) personnel. Despite ongoing efforts to promote mental health help seeking, treatment …

Multi-modal risk factors differentiate suicide attempters from ideators in military Veterans with major depressive disorder

Abstract: Background: The suicide rate for United States military veterans is 1.5× higher than that of non-veterans. To meaningfully advance suicide prevention efforts, research …

The VET STRONG powerlifting program: Increasing quality of life and perceived social support in military Veterans

Abstract: Reintegrating into civilian life presents challenges for many military veterans, who often face mental health concerns compounded by barriers to accessing care. The VET …

Successful aging in US Veterans with mental disorders: Results from the National Health and Resilience in Veterans Study

Abstract: Objectives: To determine the prevalence and correlates of successful aging in US veterans who screened positive for current major depressive disorder (MDD), generalized …

Executive functioning and anterior cingulate cortex volume as potential moderators of the combat exposure-PTSD relationship

Abstract: Combat, a common source of trauma in the military, is consistently predictive of post-traumatic stress disorder (PTSD) among service members deployed to Iraq and …

Longitudinal Oral and Fecal Microbiome Alterations in Veterans With New Antidepressant Monotherapy for Major Depressive Disorder

Abstract: Major depressive disorder (MDD) is associated with a wide range of adverse outcomes. Though antidepressants are often implemented as first-line treatments for MDD, …

Developing an individualized treatment rule for Veterans with major depressive disorder using electronic health records

Abstract: Efforts to develop an individualized treatment rule (ITR) to optimize major depressive disorder (MDD) treatment with antidepressant medication (ADM), psychotherapy, or …

Durability of deep transcranial magnetic stimulation for Veterans with treatment resistant depression with comorbid suicide risk and PTSD symptoms

Abstract: Evidence supports transcranial magnetic stimulation (TMS) as an effective treatment for symptoms of depression and PTSD; however, there has been limited investigation …

Genome-wide DNA methylation analysis in female Veterans with military sexual trauma and comorbid PTSD/MDD

Abstract: BACKGROUND: Military sexual trauma (MST) is a prevalent issue within the U.S. military. Victims are more likely to develop comorbid diseases such as posttraumatic stress …