Epidemiologic, clinical, and genetic insights into prostate cancer outcomes in Veterans

Abstract:Background: Prostate cancer, particularly metastatic castration-resistant prostate cancer (mCRPC), presents significant challenges in terms of disease management and …

Somatic tumor next-generation sequencing in US Veterans with metastatic prostate cancer

Abstract: IMPORTANCE: National guidelines recommend next-generation sequencing (NGS) of tumors in patients diagnosed with metastatic prostate cancer (mPCa) to identify potential …

Major adverse cardiovascular events among black and white Veterans receiving androgen deprivation therapy for prostate cancer: A retrospective cohort study

Abstract: Background: Androgen deprivation therapy (ADT) is the cornerstone treatment strategy for men diagnosed with high-risk prostate cancer (PC) but may increase risk for major …

Major adverse cardiovascular events among Black and White Veterans receiving androgen deprivation therapy for prostate cancer: A retrospective cohort study

Abstract: Background: Androgen deprivation therapy (ADT) is the cornerstone treatment strategy for men diagnosed with high-risk prostate cancer (PC) but may increase risk for major …

Racial and ethnic differences in prostate cancer epidemiology across disease states in the VA

Abstract: Importance: Prostate cancer (PC) care has evolved rapidly as a result of changes in prostate-specific antigen testing, novel imaging, and newer treatments. The impact of …

Effects of concurrent administration of spironolactone in Veterans with metastatic prostate cancer receiving abiraterone: A real-world retrospective study

Abstract: Introduction: Prostate cancer is the most common cancer in men in the United States with low survival rates once metastasized. Abiraterone is approved for use in …

Should military Veterans be classified as high risk for prostate cancer screening? A systematic review and meta-analysis

Abstract: Objective: To assess the unique risks of prostate cancer among U.S. veterans, and to advocate for improved care by raising awareness of the gaps in current AUA guidelines …

Germline testing for Veterans with advanced prostate cancer: Concerns about service-connected benefits

Abstract: To better understand veterans’ decisions about germline testing, we conducted a single-site, qualitative study of 32 veterans with advanced prostate cancer. Seven days …

Assessing olaparib efficacy in U.S. Veterans with metastatic prostate cancer utilizing a time-indifferent g-rate method ideal for real-world analyses

Abstract: Background: We aimed to assess real-world efficacy of the PARP inhibitor, olaparib, in US Veterans with metastatic prostate cancer (mPC) by leveraging the national data …

Real-world evidence of 18F-fluciclovine positron emission tomography/computed tomography performance for recurrent prostate cancer in the Veterans Affairs Health System

Abstract: Background: There are no population-level studies assessing (18)F-fluciclovine (fluciclovine) utilization of Positron emission tomography/computed tomography (PET/CT) for …

Healthy lifestyle and prostate cancer risk in the Million Veteran Program

Abstract: Background: This study aims to assess the impact of healthy lifestyle on prostate cancer (PCa) risk in a diverse population. Methods: Data for 281,923 men from the …

Agent Orange exposure and prostate cancer risk in the million Veteran program

Abstract: Background: The US government considers veterans to have been exposed to Agent Orange if they served in Vietnam while the carcinogen was in use, and these veterans are …